Last update
8/11/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.3
USERS' SCORE
Good
Based on 13 Reviews
8.3
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Vitamin A (Beta-Carotene, Organic Food Blend)
360 mcg
40%
Vitamin C (from Organic Food Blend)
45 mg
50%
Vitamin E (from Organic Food Blend)
6 mg
40%
Thiamin (Vitamin B1 from Organic Food Blend)
0.2 mg
17%
Riboflavin (Vitamin B2 from Organic Food Blend)
0.2 mg
15%
Niacin (from Organic Food Blend)
3 mg
19%
Vitamin B6 (from Organic Food Blend)
1 mg
59%
Folate (from Organic Food Blend)
80 mcg DFE
20%
Biotin (from Organic Food Blend)
2,500 mcg
8333%
Pantothenic Acid (from Organic Food Blend)
1 mg
20%
Zinc (from Organic Food Blend)
0.5 mg
5%
Selenium (from Organic Food Blend)
12 mcg
22%
Manganese (from Organic Food Blend)
0.1 mg
4%
Chromium (from Organic Food Blend)
35 mcg
100%
Silica (from Organic Bamboo Extract, standardized to 75% Silica)
10 mg
+
Organic Food BlendOrganic Sesbania grandiflora (leaf), Organic Amla Berry (fruit), Organic Apple (fruit), Organic Guava (fruit &leaf), Organic Annatto (fruit & seed), Organic Holy Basil (leaf), Organic Lemon (fruit & peel), Organic Moringa (leaf), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Cherry (fruit), Organic Blackberry (fruit), Organic Green Bell Pepper (fruit), Organic Brussels Sprout (leaf), Organic Ginger (root), Organic Blueberry (fruit), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
710 mg
+
Organic Beauty BlendOrganic Green Tea Extract (leaf), Organic Pomegranate Extract [standardized to 50% Polyphenols] (fruit), Organic Citrus Bioflavonoids (fruit & peel), Organic Rooibos Extract (leaf), Organic Bamboo Extract (shoot)
194 mg
+
Organic Turmeric (root)
50 mg
+
Top Medical Research Studies
9
We explored the effects of decoction (GSZD) on bone erosion linked to rheumatoid arthritis (RA) in a rat model. Our study involved various groups receiving either GSZD or standard treatments, monitoring changes in paw volume and arthritic severity.
The findings showed that GSZD significantly improved inflammatory symptoms and reduced joint tissue erosion. It decreased markers of osteoclasts and enhanced protective factors, suggesting promising potential for GSZD as a supplement in treating RA without pronounced adverse effects.
The findings showed that GSZD significantly improved inflammatory symptoms and reduced joint tissue erosion. It decreased markers of osteoclasts and enhanced protective factors, suggesting promising potential for GSZD as a supplement in treating RA without pronounced adverse effects.
Read More
8
We investigated the efficacy of a petroleum ether extract from the hips of Rosa multiflora in treating collagen-induced arthritis in rats. The study used a control group, treated with various doses of the extract, and compared it against a well-known medication.
The results showed that the highest dose effectively reduced arthritis severity and paw swelling. It also appeared to inhibit inflammation markers and boost antioxidant enzyme levels. However, the precise mechanisms of how the extract works and its key components need further research.
The results showed that the highest dose effectively reduced arthritis severity and paw swelling. It also appeared to inhibit inflammation markers and boost antioxidant enzyme levels. However, the precise mechanisms of how the extract works and its key components need further research.
Read More
8
We assessed the effects of collagen supplements, specifically strain CCFM1074, on arthritis in rats. This study utilized a robust method that examined the immune responses, gut microbiota, and various metabolites.
Our findings revealed that CCFM1074 successfully reduced symptoms of arthritis, enhancing beneficial immune responses while modulating gut microbiota and metabolites. Meanwhile, another strain, CCFM1075, did not show significant benefits.
Overall, CCFM1074 appears to balance immune functions and improve gut health, suggesting its potential role in managing autoimmune disorders.
Our findings revealed that CCFM1074 successfully reduced symptoms of arthritis, enhancing beneficial immune responses while modulating gut microbiota and metabolites. Meanwhile, another strain, CCFM1075, did not show significant benefits.
Overall, CCFM1074 appears to balance immune functions and improve gut health, suggesting its potential role in managing autoimmune disorders.
Read More
Most Useful Reviews
7.5
Joint pain relief
8 people found this helpful
While searching for a collagen replenishment product for my autoimmune disorder, I tried this Collagen builder from my favourite, Garden of Life. Within a week, I noticed that my joints—knees, shoulders, etc.—stopped crunching and hurting! An added benefit for me is the improvement in my skin's condition; it has become even and elastic. I now take it regularly, as my condition leaves me with a constant deficiency of vitamins.
Read More
9
Skin elasticity improved
85 people found this helpful
This is my valuable find! Girls, this is a wonderful supplement, and I sincerely recommend you try it. Collagen and elastin decrease with age, and after 30-35, the skin loses elasticity. I am 34, and although I have no visible wrinkles, my beautician advised me to take this supplement for prevention. After a month of use, my skin is noticeably improved, both on my face and body. Dry elbows and heels are now no longer a problem. I'm definitely continuing with this regimen and will order for my mum as well, as collagen and elastin are essential for skin and ligaments.
Read More
7.5
Hair growth improved
42 people found this helpful
I ordered one package to test as I was concerned about allergies, but my body accepted it well. Within a couple of weeks, I noticed my hair had stopped falling out as drastically, and new growth was visible! My nails seem healthier as well, though the skin is peeling, which may relate to the weather. I was drawn to this vegan product that promotes collagen production. I'll definitely order more since the results are undeniable!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.3
- All Researches
9
We explored how the collagen supplement BD400 affects rheumatoid arthritis (RA) using a collagen-induced arthritis rat model.
Our findings indicated that BD400 significantly reduced arthritis symptoms, including joint swelling and inflammation. It also positively influenced gut health by restoring intestinal permeability and altering gut microbiota composition.
Ultimately, our study suggests that BD400 can slow the progression of RA by down-regulating certain inflammatory factors and enhancing gut barrier function, presenting an interesting potential for autoimmune disorder management.
Our findings indicated that BD400 significantly reduced arthritis symptoms, including joint swelling and inflammation. It also positively influenced gut health by restoring intestinal permeability and altering gut microbiota composition.
Ultimately, our study suggests that BD400 can slow the progression of RA by down-regulating certain inflammatory factors and enhancing gut barrier function, presenting an interesting potential for autoimmune disorder management.
Read More
9
We explored the effects of decoction (GSZD) on bone erosion linked to rheumatoid arthritis (RA) in a rat model. Our study involved various groups receiving either GSZD or standard treatments, monitoring changes in paw volume and arthritic severity.
The findings showed that GSZD significantly improved inflammatory symptoms and reduced joint tissue erosion. It decreased markers of osteoclasts and enhanced protective factors, suggesting promising potential for GSZD as a supplement in treating RA without pronounced adverse effects.
The findings showed that GSZD significantly improved inflammatory symptoms and reduced joint tissue erosion. It decreased markers of osteoclasts and enhanced protective factors, suggesting promising potential for GSZD as a supplement in treating RA without pronounced adverse effects.
Read More
8
We assessed the effects of collagen supplements, specifically strain CCFM1074, on arthritis in rats. This study utilized a robust method that examined the immune responses, gut microbiota, and various metabolites.
Our findings revealed that CCFM1074 successfully reduced symptoms of arthritis, enhancing beneficial immune responses while modulating gut microbiota and metabolites. Meanwhile, another strain, CCFM1075, did not show significant benefits.
Overall, CCFM1074 appears to balance immune functions and improve gut health, suggesting its potential role in managing autoimmune disorders.
Our findings revealed that CCFM1074 successfully reduced symptoms of arthritis, enhancing beneficial immune responses while modulating gut microbiota and metabolites. Meanwhile, another strain, CCFM1075, did not show significant benefits.
Overall, CCFM1074 appears to balance immune functions and improve gut health, suggesting its potential role in managing autoimmune disorders.
Read More
8
We examined the anti-inflammatory properties of liposome/gold hybrid nanoparticles that contain Coenzyme Q10 (LGNP-CoQ10) in a model of rheumatoid arthritis in mice. Over 10 weeks, we treated the mice with LGNP-CoQ10 and noted that it significantly reduced inflammation and levels of specific pro-inflammatory factors.
Moreover, the treatment showed a decrease in pro-inflammatory cell populations, indicating a reduced inflammatory response that could benefit those suffering from rheumatoid arthritis. Our findings highlight the promising therapeutic potential of LGNP-CoQ10 in managing inflammatory autoimmune disorders.
Moreover, the treatment showed a decrease in pro-inflammatory cell populations, indicating a reduced inflammatory response that could benefit those suffering from rheumatoid arthritis. Our findings highlight the promising therapeutic potential of LGNP-CoQ10 in managing inflammatory autoimmune disorders.
Read More
8
We explored how Hsp65, a protein delivered by beneficial bacteria, can help prevent arthritis in mice. In our study, continuous delivery in the gut led to the creation of regulatory T cells that successfully blocked the onset of arthritis. We observed reduced clinical signs of arthritis and lower inflammation markers, like IL-17 and anti-collagen antibodies. This approach appears to modify gut bacteria and enhance immune tolerance, suggesting Hsp65 could potentially be a new tool for treating autoimmune diseases.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Joint pain relief
8 people found this helpful
While searching for a collagen replenishment product for my autoimmune disorder, I tried this Collagen builder from my favourite, Garden of Life. Within a week, I noticed that my joints—knees, shoulders, etc.—stopped crunching and hurting! An added benefit for me is the improvement in my skin's condition; it has become even and elastic. I now take it regularly, as my condition leaves me with a constant deficiency of vitamins.
Read More
9
Skin elasticity improved
85 people found this helpful
This is my valuable find! Girls, this is a wonderful supplement, and I sincerely recommend you try it. Collagen and elastin decrease with age, and after 30-35, the skin loses elasticity. I am 34, and although I have no visible wrinkles, my beautician advised me to take this supplement for prevention. After a month of use, my skin is noticeably improved, both on my face and body. Dry elbows and heels are now no longer a problem. I'm definitely continuing with this regimen and will order for my mum as well, as collagen and elastin are essential for skin and ligaments.
Read More
7.5
Hair growth improved
42 people found this helpful
I ordered one package to test as I was concerned about allergies, but my body accepted it well. Within a couple of weeks, I noticed my hair had stopped falling out as drastically, and new growth was visible! My nails seem healthier as well, though the skin is peeling, which may relate to the weather. I was drawn to this vegan product that promotes collagen production. I'll definitely order more since the results are undeniable!
Read More
9
Hair loss decreased
4 people found this helpful
There is an effect! I saw improvements and ordered another can. My hair loss has significantly reduced, and I haven’t experienced such results for a long time. This has been my salvation!
Read More
7.5
Skin improvement
4 people found this helpful
A rescue for vegans! I ordered this supplement because, at 30, collagen is essential, but vegan options are scarce. This excellent alternative stimulates the production of my own collagen. The results aren't noticeable immediately, but after using almost the entire jar, I've seen improvements in my skin, nails, and hair. I will definitely order more.
Read More
Frequently Asked Questions
7.5
Joint pain relief
8 people found this helpful
While searching for a collagen replenishment product for my autoimmune disorder, I tried this Collagen builder from my favourite, Garden of Life. Within a week, I noticed that my joints—knees, shoulders, etc.—stopped crunching and hurting! An added benefit for me is the improvement in my skin's condition; it has become even and elastic. I now take it regularly, as my condition leaves me with a constant deficiency of vitamins.
7.5
Skin elasticity enhanced
3 people found this helpful
I adore this vegan collagen builder! Over the last two years, I noticed my skin was losing elasticity and fine wrinkles began to appear. After about two weeks of use, I saw positive changes: my skin's turgor improved, I had a blush, and wrinkles were less visible. Although the tablets are sizable, they are manageable to swallow. If my review was helpful, I'd appreciate a kind rating.
9
Skin elasticity improved
85 people found this helpful
This is my valuable find! Girls, this is a wonderful supplement, and I sincerely recommend you try it. Collagen and elastin decrease with age, and after 30-35, the skin loses elasticity. I am 34, and although I have no visible wrinkles, my beautician advised me to take this supplement for prevention. After a month of use, my skin is noticeably improved, both on my face and body. Dry elbows and heels are now no longer a problem. I'm definitely continuing with this regimen and will order for my mum as well, as collagen and elastin are essential for skin and ligaments.
7.5
Autoimmune impact noted
4 people found this helpful
It seems effective for hair loss! I dealt with significant hair loss and due to my autoimmune disorder, I decided to try this. After finishing a bottle, I noticed my hair loss returned when I stopped taking it, prompting me to repurchase. I hope it will be beneficial for both my hair loss and my autoimmune condition in the long run.
9
Post-COVID support
I've been using this for nearly two months and have already ordered my second bottle. Honestly, I felt a major improvement in my skin, nails, and hair after three weeks. Additionally, it helped with my post-COVID symptoms after I contracted the virus. Highly recommended!
7
Skin moisturised
1 people found this helpful
There is a noticeable effect! I purchased this on a friend’s recommendation, and after almost two weeks, my skin feels fresher, with no dryness or stomach issues when taking it. I will certainly reorder!
7.5
Hair growth improved
42 people found this helpful
I ordered one package to test as I was concerned about allergies, but my body accepted it well. Within a couple of weeks, I noticed my hair had stopped falling out as drastically, and new growth was visible! My nails seem healthier as well, though the skin is peeling, which may relate to the weather. I was drawn to this vegan product that promotes collagen production. I'll definitely order more since the results are undeniable!
7.5
Skin improvement
4 people found this helpful
A rescue for vegans! I ordered this supplement because, at 30, collagen is essential, but vegan options are scarce. This excellent alternative stimulates the production of my own collagen. The results aren't noticeable immediately, but after using almost the entire jar, I've seen improvements in my skin, nails, and hair. I will definitely order more.
7.5
Improved skin health
1 people found this helpful
I will order more... I really liked the vitamins and intend to continue taking them. However, I believe that one package isn't sufficient; for a complete course, two are necessary. I noticed much less hair loss and an improvement in my skin condition. I trust the manufacturer and would like to try other products from the same company.
9
We explored how the collagen supplement BD400 affects rheumatoid arthritis (RA) using a collagen-induced arthritis rat model.
Our findings indicated that BD400 significantly reduced arthritis symptoms, including joint swelling and inflammation. It also positively influenced gut health by restoring intestinal permeability and altering gut microbiota composition.
Ultimately, our study suggests that BD400 can slow the progression of RA by down-regulating certain inflammatory factors and enhancing gut barrier function, presenting an interesting potential for autoimmune disorder management.
Our findings indicated that BD400 significantly reduced arthritis symptoms, including joint swelling and inflammation. It also positively influenced gut health by restoring intestinal permeability and altering gut microbiota composition.
Ultimately, our study suggests that BD400 can slow the progression of RA by down-regulating certain inflammatory factors and enhancing gut barrier function, presenting an interesting potential for autoimmune disorder management.
8
We assessed the effects of collagen supplements, specifically strain CCFM1074, on arthritis in rats. This study utilized a robust method that examined the immune responses, gut microbiota, and various metabolites.
Our findings revealed that CCFM1074 successfully reduced symptoms of arthritis, enhancing beneficial immune responses while modulating gut microbiota and metabolites. Meanwhile, another strain, CCFM1075, did not show significant benefits.
Overall, CCFM1074 appears to balance immune functions and improve gut health, suggesting its potential role in managing autoimmune disorders.
Our findings revealed that CCFM1074 successfully reduced symptoms of arthritis, enhancing beneficial immune responses while modulating gut microbiota and metabolites. Meanwhile, another strain, CCFM1075, did not show significant benefits.
Overall, CCFM1074 appears to balance immune functions and improve gut health, suggesting its potential role in managing autoimmune disorders.
9
We explored the effects of decoction (GSZD) on bone erosion linked to rheumatoid arthritis (RA) in a rat model. Our study involved various groups receiving either GSZD or standard treatments, monitoring changes in paw volume and arthritic severity.
The findings showed that GSZD significantly improved inflammatory symptoms and reduced joint tissue erosion. It decreased markers of osteoclasts and enhanced protective factors, suggesting promising potential for GSZD as a supplement in treating RA without pronounced adverse effects.
The findings showed that GSZD significantly improved inflammatory symptoms and reduced joint tissue erosion. It decreased markers of osteoclasts and enhanced protective factors, suggesting promising potential for GSZD as a supplement in treating RA without pronounced adverse effects.
References
- Yang Y, Hong Q, Zhang X, Liu Z. BD400 protects from collagen-induced arthritis through histidine metabolism. Front Immunol. 2025;16:1518181. 10.3389/fimmu.2025.1518181
- Fan Z, Ross RP, Stanton C, Hou B, Zhao J, et al. CCFM1074 Alleviates Collagen-Induced Arthritis in Rats Balancing Treg/Th17 and Modulating the Metabolites and Gut Microbiota. Front Immunol. 2021;12:680073. 10.3389/fimmu.2021.680073
- Wei SJ, Zhang Q, Xiang YJ, Peng LY, Peng W, et al. decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF-κB signalling to suppress osteoclastogenesis. Pharm Biol. 2021;59:262. 10.1080/13880209.2021.1876100
- Jhun J, Moon J, Ryu J, Shin Y, Lee S, et al. Liposome/gold hybrid nanoparticle encoded with CoQ10 (LGNP-CoQ10) suppressed rheumatoid arthritis via STAT3/Th17 targeting. PLoS One. 2020;15:e0241080. 10.1371/journal.pone.0241080
- Gusmao-Silva G, Aguiar SLF, Miranda MCG, Guimarães MA, Alves JL, et al. Hsp65-Producing Prevents Antigen-Induced Arthritis in Mice. Front Immunol. 2020;11:562905. 10.3389/fimmu.2020.562905
- Wu J, Liu X, Chan CO, Mok DK, Chan SW, et al. Petroleum ether extractive of the hips of Rosa multiflora ameliorates collagen-induced arthritis in rats. J Ethnopharmacol. 2014;157:45. 10.1016/j.jep.2014.09.026
- Nowak B, Ciszek-Lenda M, Sróttek M, Gamian A, Kontny E, et al. Lactobacillus rhamnosus exopolysaccharide ameliorates arthritis induced by the systemic injection of collagen and lipopolysaccharide in DBA/1 mice. Arch Immunol Ther Exp (Warsz). 2012;60:211. 10.1007/s00005-012-0170-5
